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Gastrointestinal (GI) Panel - Genetic Testing for Digestive Issues

It has become increasingly clear over the past few years that gastrointestinal function and environment can have a tremendous impact on your overall health. The gastrointestinal system is complex and has a number of previously unknown roles in the stability of brain function and immune stabilization. As with all of our panels at GX Sciences, this panel is designed to provide a scientifically validated system to indicate the need for a specific supplement or medication based on an individual’s genetic profile.

Understanding “the Gut”

The gastrointestinal tract, or gut, is an organ system consisting of the mouth, esophagus, stomach, small intestine, pancreas, liver, gallbladder, colon, and rectum. The gut is unique in that it’s the only organ system that is autonomic, functioning without oversight from the brain. It’s primary purpose is to ingest food and drink, absorb its nutrients for energy, and expel the remaining materials from the body. The gut also serves as a key part of the immune system.

There is a major immunological presence around the gut. As the GI tract introduces only foreign organisms (like bacteria and viruses), the gut is a likely place for contamination. To combat the inherent risk, 70% of the immune system surrounds the gut to protect the whole body from getting sick. Since the support of brain function, immune stabilization, and digestive process are dependent on the chemical processes occurring in and around the gut, aiding the cells and good bacteria that carry out the mechanisms can help overall health.

The Areas of Improvement for Better Gastrointestinal Health

The Gastrointestinal Panel is indicated for patients with:

  • IBS
  • Chronic Constipation
  • Chronic Diarrhea
  • Intermittent Intestinal Pain
  • Mast Cell Disorder
  • Chronic Reflux
  • Recurrent Intestinal Infection
  • Numerous Food Allergies

Dr. Stewart explains how the GI panel is helpful for patients with food intolerance and bowel problems.
Listen to Dr. Stewart explain how the gut and brain are tied together and affect each other's function.


Environmental Inflammation

Histamine is a chemical compound in the immune system that helps rid the body of allergens by triggering physiological functions like inflammation. The immune system uses inflammation to help the body repair, but when inflammation is unchecked, it can do more damage than good. Foods like tomatoes, spinach, citrus fruits, and fermented drinks are high in histamines. While considered part of a healthy diet for many, these high-histamine foods can be harmful to those without the enzyme or enzymes necessary to break down histamines and control inflammation. Neurobiologix’s GI His Support is intended to improve histamine tolerance. The results of your gastrointestinal panel will show whether or not your DNA indicates a poor ability to break down external histamines. If this is the case, taking GI His Support before or during a meal and avoiding foods containing histamines can help with histamine intolerance. Probiotics can also reduce inflammation by promoting and/or supporting a healthy gut microbiome by introducing good bacteria, and Beta Glucans can help kill bad bacteria to further reduce inflammation.

Gluten & Lactose Intolerance

Chronic inflammation can also occur as a result of gluten ingestion for those that are gluten-sensitive or intolerant. Our genetic test for gastrointestinal issues can identify those genetically inclined to have problems with gluten. Lactose intolerance is another gastrointestinal-related disorder. Lactose is a sugar found in milk that is broken down by the enzyme lactase. Those with lactose intolerance do not have enough lactase enzymes to properly digest it, which results in intestinal distress. Some people produce little to no lactase because of their inherited genes, making it identifiable through a DNA submission.

DNA Testing for GI / Stomach Issues

The GX Sciences Gastrointestinal Panel consists of 12 gene variants (SNPs) that have been chosen by our medical experts which play a significant role in the:

o Breakdown of Histamines found in food sources

o Individual need for Probiotics

o Gluten Sensitivity and Celiac Risk

o Autophagy function in Immune Clearance of Intestinal Pathogens

Utilizing our proprietary SNP Genius software, the Gastrointestinal Panel will take an individual patient’s DNA genetic findings and interpret them through the GX Sciences Precision Supplementation algorithm to determine the exact therapeutic need of the patient. Gut microbiome testing can be costly, ranging from $300-400. Our GI genetic test can indicate to those with extreme GI issues whether or not more extensive food allergy and/or microbiome testing is needed.