Pharmaco Genomic testing, otherwise known as PGx, refers to a type of genetic test by cheek swab to predict a patient's likelihood to experience an adverse event or not respond to a given drug. Genetic variation in metabolism may result in high concentrations of drugs and an increased risk of adverse effects in slow metabolizers, which is important when using, for example, antidepressants or pain medication.
Just as there are known drug-drug interactions, there are also known drug-gene interactions. Pharmacogenomics is the study of how a personís genes affect their response to specific medications. It is a type of precision medicine that GX Sciences offers our providers' patients at an affordable cash price. Log in to your GX provider account to obtain pricing and order for a patient.
What our GX Sciences PGx report offers is:
- Your patient a customized report
- 7-10 day turnaround from when order is placed via our website
- Report generated by the Gene Dose Liveô software
To view a copy of our report click on the link: http://gxsciences.com/v/vspfiles/downloadables/GX_PGX_CLSExample-report-042318.pdf
Currently, the FDA includes pharmacogenomic warnings on the labels of more than 200 medications.* A one-time cheew swab test lets providers know whether a patient has specific genetic variants. This knowledge can influence dosing and the choice of medication. It can also alert physicians to avoid specific drugs.
NOTE: If we already have the patient's swab from a previous order then an additional swab is NOT needed. Fill out a requisition form for the patient and provider to sign and make payment via online by choosing "Provider Payment" and selecting Pharmaco Genomic Test.
Pre and Post-Surgical Pharmacogenomic Testing
Many patients spend only a few days preparing their bodies before a major surgery. Staying hydrated and eating a healthy diet are important pre-surgery precautions, but providing your body all the necessary nutrients for recovery can be of equal importance. Additionally, understanding individual reactions to pharmaceuticals such as anesthesia and antibiotics can be a considerable asset in ensuring a smooth procedure. Pharmacogenomic testing is a new technique used by physicians to assess an individualís genome to determine how he/she will react to various drugs and doses. It may help prevent adverse drug events (ADEs), or bad reactions to medication, which account for nearly 700,000 hospital visits per year.
What is pharmacogenomic testing?
Pharmaceuticals have traditionally been developed using a one-size-fits-most approach with the assumption that medications work the same way regardless of the person taking them. This forces most people to engage in a trial and error process to find the best medicine. Pharmacogenomic testing is already recommended by the FDA to assist with prescribing medication for the treatment of HIV, colon cancer, and acute lymphoblastic leukemia. The demand for pharmacogenomic testing is only expected to increase as researchers discover the potential of personalized medicine and the possibility of new drug development.
What role does pharmacogenomic testing play in major surgical procedures?
Itís no secret that surgical procedures cost Americans billions of dollars each year. This includes both medically necessary and elective cosmetic procedures. Such a large investment in your health or beauty requires considerable care and preparation to achieve the desired results. Your body undergoes intense upset during surgery, and a one-time pharmacogenomic test can assist in determining how well your body clears toxins. This can influence the anesthesia chosen and the dose to administer, as well as the specific nutrients you need to prepare and recover. For example, glutathione might be recommended to take before a procedure to boost the immune system. Surgery also causes inflammation, a normal bodily response; however, inflammation control is absolutely necessary for a successful recovery. GX Sciences also offers an Inflammatory Panel to test your bodyís reaction to inflammation.
Who should get a pharmacogenomic panel?
For those wanting to reduce the time and money needed for trial and error medications, a pharmacogenomic test may be the perfect aid to your prescription. Information about your genetic makeup may be the greatest weapon against a particular ailment or invasive procedure. If you have been frustrated with your lack of success with various prescription drugs, the answer may lie within your genes. Pharmacogenomic testing can be used for multiple purposes; assessing specific genes allows you to learn more about yourself and how your body responds to foreign substances.
Personalized treatment as the future of medicine
Medication is not one-size-fits-all, and it can be difficult to determine what your body will respond to. Major surgery requires more preparation than just a few days of drinking water, and assuring that your body has everything it needs to make a speedy recovery is of the utmost importance. Pharmacogenomic testing may reveal new information that is useful to your health and your future surgical procedures.